Newest publications
Conformation-specific monoclonal antibodies reveal early Tau structural intermediates in Alzheimer's disease
Grigoria Tsaka, Aida Montserrat Pagès, Cristiano Brás De Sousa, Jeroen Lammertyn, Grzegorz Walkiewic, Luis Aragão Gomes, Maya Imbrechts, Sophie Tops, Rajasekhar Kolla, Kevin Muwonge, Rik Vandenberghe, Karen Vanhoorelbeke, Christine A F von Arnim, Nick Geukens, Frederic Rousseau, Joost Schymkowitz, Dragana Spasic, Dietmar Rudolf Thal, Debby Thomas, Joris Winderickx
J Biol Chem . 2026 Feb 3
PubMedIn silico design of stable single-domain antibodies with high affinity
Zhongyao Zhang, Rob van der Kant, Iva Marković, David Vizarraga, Teresa Garcia, Katerina Maragkou, Javier Delgado Blanco, Damiano Cianferoni, Gabriele Orlando, Gabriel Cia, Nick Geukens, Carlo Carolis, Alexander N Volkov, Savvas N Savvides, Maarten Dewilde, Joost Schymkowitz, Luis Serrano Pubul, Frederic Rousseau
Structure . 2026 Jan 9
PubMedEnergetic profiling reveals thermodynamic principles underlying amyloid fibril maturation
Ramon Duran-Romaña, Joost Schymkowitz, Frederic Rousseau, Nikolaos Louros
Nat Commun 2025 Nov 18
PubMedA versatile platform for combinatorial antibody library cloning and NGS-based quality control with high accuracy
Zhongyao Zhang, Simon D'Hondt, Rob Van der Kant, Guy Hermans, Nick Geukens, Vitor Bernardes Pinheiro, Joost Schymkowitz, Frederic Rousseau, Maarten Dewilde
Nucleic Acids Res . 2025 Oct 14
PubMedToward a thermodynamic taxonomy of amyloid fibrils
Nikolaos Louros, Joost Schymkowitz, Frederic Rousseau
Structure 2025 Oct 2
PubMed[11C]HSP990 PET as a translational tool to investigate the role of Hsp90 in tumours and support the development of Hsp90 therapeutics
Romy Cools, Valeria Narykina, Koen Vermeulen, Sanket J Mishra, Brian S J Blagg, Marleen Derweduwe, Frederik De Smet, Aaron Ziani-Zeryouh, Matteo Riva, An Coosemans, Frederic Rousseau, Joost Schymkowitz, Guy Bormans
EJNMMI Radiopharm Chem. 2025 Sep 26
PubMed
