Sample prep

Nuclera eProtein Discovery

The eProtein Discovery™ technology from Nuclera is a cutting-edge platform that enables researchers to synthesize and screen proteins rapidly and efficiently.

The instrument uses Electrowetting on Dielectric technology (EWOD) which allows for miniaturized, high-throughput screening of up to 24 different DNA constructs in the soluble protein workflow. Nuclera has recently expanded eProtein Discovery with a new membrane protein workflow, enabling the expression, purification and stabilization (through nanodiscs for example) of even the most challenging membrane proteins that are targets in therapeutic development.

Key Features:

• Based on cell-free protein synthesis innovation (CFPS) which utilizes linear DNAs (eGene™ constructs) as one of its ingredients to power the cell-free machinery to produce protein.
• Screening of up to 192 unique combinations of expression conditions.
• Delivering reliable proteins in-hand in 48 hours.
• The software automatically processes the parameters such as expected protein yield and solubility per combination.
• Scale up kits available to produce more proteins for assays that require higher quantities.