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    The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation

    Anita Pras, Bert Houben, Francesco A Aprile, Renée Seinstra, Rodrigo Gallardo, Leen Janssen, Wytse Hogewerf, Christian Gallrein, Matthias De Vleeschouwer, Alejandro Mata-Cabana, Mandy Koopman, Esther Stroo, Minke de Vries, Samantha Louise Edwards, Janine Kirstein, Michele Vendruscolo, Salvatore Fabio Falsone, Frederic Rousseau, Joost Schymkowitz, Ellen A A Nollen
    EMBO J . 2021 Oct 7;e107568
    PubMed
  • publication

    Protein structure and aggregation: a marriage of necessity ruled by aggregation gatekeepers

    Bert Houben, Frederic Rousseau, Joost Schymkowitz
    Trends Biochem Sci . 2021 Sep
    PubMed
  • publication

    Synthetic Pept-Ins as a Generic Amyloid-Like Aggregation-Based Platform for In Vivo PET Imaging of Intracellular Targets

    Maxime Siemons, Kaat Luyten, Ladan Khodaparast, Laleh Khodaparast, Joan Lecina, Filip Claes, Rodrigo Gallardo, Michel Koole, Meine Ramakers, Joost Schymkowitz, Guy Bormans, Frederic Rousseau
    Bioconjug Chem . 2021 Sep 15
    PubMed
  • publication

    The Dynamic Transition of Persistence toward the Viable but Nonculturable State during Stationary Phase Is Driven by Protein Aggregation

    Liselot Dewachter, Celien Bollen, Dorien Wilmaerts, Elen Louwagie, Pauline Herpels, Paul Matthay, Ladan Khodaparast, Laleh Khodaparast, Frederic Rousseau, Joost Schymkowitz, Jan Michiels
    mBio . 2021 Aug 3
    PubMed
  • publication

    Gene Erosion Can Lead to Gain-of-Function Alleles That Contribute to Bacterial Fitness

    Julien Mortier, Elisa Gayán, Ronald Van Eyken, Oscar Enrique Torres Montaguth, Ladan Khodaparast, Laleh Khodaparast, Bert Houben, Sebastien Carpentier, Frederic Rousseau, Joost Schymkowitz, Abram Aertsen
    mBio. 2021 Jul 6;e0112921
    PubMed
  • publication

    Bacterial Protein Homeostasis Disruption as a Therapeutic Intervention

    Laleh Khodaparast, Guiqin Wu, Ladan Khodaparast, Béla Z Schmidt, Frederic Rousseau, Joost Schymkowitz
    Frontiers in Molecular Bioscience 2021 Jun 2;8:681855
    PubMed