Newest publications
Repurposing the antidepressant sertraline as SHMT inhibitor to suppress serine/glycine synthesis addicted breast tumor growth
Shauni Lien Geeraerts, Kim Rosalie Kampen, Gianmarco Rinaldi, Purvi Gupta, Melanie Planque, Nikolaos Louros, Elien Heylen, Kaat De Cremer, Katrijn De Brucker, Stijn Vereecke, Benno Verbelen, Pieter Vermeersch, Joost Schymkowitz, Frederic Rousseau, David Cassiman, Sarah-Maria Fendt, Arnout Voet, Bruno P A Cammue, Karin Thevissen, Kim De Keersmaecker
Mol Cancer Ther . 2020 Nov 17
PubMedThe structural basis for an on-off switch controlling Gβγ-mediated inhibition of TRPM3 channels
Marc Behrendt, Fabian Gruss, Raissa Enzeroth, Sandeep Dembla, Siyuan Zhao, Pierre-Antoine Crassous, Florian Mohr, Mieke Nys, Nikolaos Louros, Rodrigo Gallardo, Valentina Zorzini, Doris Wagner, Anastassios Economou, Frederic Rousseau, Joost Schymkowitz, Stephan E Philipp, Tibor Rohacs, Chris Ulens, Johannes Oberwinkler
Proc Natl Acad Sci U S A . 2020 Oct 29
PubMedDrying mode and hydrothermal treatment conditions govern the formation of amyloid-like protein fibrils in solutions of dried hen egg white
MargaritaMonge-Morera, Marlies A. Lambrecht, Lomme J. Deleu, Thibault Godefroidt, Peter Goos, Frederic Rousseau, Joost Schymkowitz, Jan A. Delcour
Food Hydrocolloids Volume 112
Potential human transmission of amyloid β pathology: surveillance and risks
Elsa Lauwers, Giovanna Lalli, Sebastian Brandner, John Collinge, Veerle Compernolle, Charles Duyckaerts, Gustaf Edgren, Stéphane Haïk, John Hardy, Adel Helmy , Adrian J Ivinson, Zane Jaunmuktane , Mathias Jucker, Richard Knight, Robin Lemmens, I-Chun Lin, Seth Love, Simon Mead, V Hugh Perry, James Pickett, Guy Poppy, Sheena E Radford, Frederic Rousseau, Carol Routledge, Giampietro Schiavo, Joost Schymkowitz, Dennis J Selkoe, Colin Smith, Dietmar R Thal, Tom Theys, Pierre Tiberghien, Peter van den Burg, Philippe Vandekerckhove, Clare Walton, Hans L Zaaijer, Henrik Zetterberg, Bart De Strooper
Review Lancet Neurol
PubMedStructure-based machine-guided mapping of amyloid sequence space reveals uncharted sequence clusters with higher solubilities
Nikolaos Louros, Gabriele Orlando, Matthias De Vleeschouwer, Frederic Rousseau, Joost Schymkowitz
Nature Communications 11 (1):3314.
PubMedProcessing Induced Changes in Food Proteins: Amyloid Formation During Boiling of Hen Egg White
Margarita Monge-Morera, Marlies A Lambrecht, Lomme J Deleu, Rodrigo Gallardo, Nikolaos N Louros, Matthias De Vleeschouwer, Frederic Rousseau, Joost Schymkowitz, Jan A Delcour
Biomacromolecules 21 (6):2218-2228.
PubMed
