Newest publications
Heterotypic interactions in amyloid function and disease
Katerina Konstantoulea, Nikolaos Louros, Frederic Rousseau, Joost Schymkowitz
FEBS J
PubMedInvestigating the mechanism of action of aggregation-inducing antimicrobial Pept-ins
Guiqin Wu, Laleh Khodaparast, Ladan Khodaparast, Matthias De Vleeschouwer, Joëlle Housmans, Bert Houben, Joost Schymkowitz, Frederic Rousseau
Cell Chem Biol
PubMedMechanisms and therapeutic potential of interactions between human amyloids and viruses
Emiel Michiels, Frederic Rousseau, Joost Schymkowitz
Cell Mol Life Sci . 2020 Nov 26;1-17
PubMedRepurposing the antidepressant sertraline as SHMT inhibitor to suppress serine/glycine synthesis addicted breast tumor growth
Shauni Lien Geeraerts, Kim Rosalie Kampen, Gianmarco Rinaldi, Purvi Gupta, Melanie Planque, Nikolaos Louros, Elien Heylen, Kaat De Cremer, Katrijn De Brucker, Stijn Vereecke, Benno Verbelen, Pieter Vermeersch, Joost Schymkowitz, Frederic Rousseau, David Cassiman, Sarah-Maria Fendt, Arnout Voet, Bruno P A Cammue, Karin Thevissen, Kim De Keersmaecker
Mol Cancer Ther . 2020 Nov 17
PubMedThe structural basis for an on-off switch controlling Gβγ-mediated inhibition of TRPM3 channels
Marc Behrendt, Fabian Gruss, Raissa Enzeroth, Sandeep Dembla, Siyuan Zhao, Pierre-Antoine Crassous, Florian Mohr, Mieke Nys, Nikolaos Louros, Rodrigo Gallardo, Valentina Zorzini, Doris Wagner, Anastassios Economou, Frederic Rousseau, Joost Schymkowitz, Stephan E Philipp, Tibor Rohacs, Chris Ulens, Johannes Oberwinkler
Proc Natl Acad Sci U S A . 2020 Oct 29
PubMedDrying mode and hydrothermal treatment conditions govern the formation of amyloid-like protein fibrils in solutions of dried hen egg white
MargaritaMonge-Morera, Marlies A. Lambrecht, Lomme J. Deleu, Thibault Godefroidt, Peter Goos, Frederic Rousseau, Joost Schymkowitz, Jan A. Delcour
Food Hydrocolloids Volume 112