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    Synthetic Pept-Ins as a Generic Amyloid-Like Aggregation-Based Platform for In Vivo PET Imaging of Intracellular Targets

    Maxime Siemons, Kaat Luyten, Ladan Khodaparast, Laleh Khodaparast, Joan Lecina, Filip Claes, Rodrigo Gallardo, Michel Koole, Meine Ramakers, Joost Schymkowitz, Guy Bormans, Frederic Rousseau
    Bioconjug Chem . 2021 Sep 15
    PubMed
  • publication

    The Dynamic Transition of Persistence toward the Viable but Nonculturable State during Stationary Phase Is Driven by Protein Aggregation

    Liselot Dewachter, Celien Bollen, Dorien Wilmaerts, Elen Louwagie, Pauline Herpels, Paul Matthay, Ladan Khodaparast, Laleh Khodaparast, Frederic Rousseau, Joost Schymkowitz, Jan Michiels
    mBio . 2021 Aug 3
    PubMed
  • publication

    Gene Erosion Can Lead to Gain-of-Function Alleles That Contribute to Bacterial Fitness

    Julien Mortier, Elisa Gayán, Ronald Van Eyken, Oscar Enrique Torres Montaguth, Ladan Khodaparast, Laleh Khodaparast, Bert Houben, Sebastien Carpentier, Frederic Rousseau, Joost Schymkowitz, Abram Aertsen
    mBio. 2021 Jul 6;e0112921
    PubMed
  • publication

    Bacterial Protein Homeostasis Disruption as a Therapeutic Intervention

    Laleh Khodaparast, Guiqin Wu, Ladan Khodaparast, Béla Z Schmidt, Frederic Rousseau, Joost Schymkowitz
    Frontiers in Molecular Bioscience 2021 Jun 2;8:681855
    PubMed
  • publication

    In-silico prediction of in-vitro protein liquid-liquid phase separation experiments outcomes with multi-head neural attention

    Daniele Raimondi, Gabriele Orlando, Emiel Michiels, Donya Pakravan, Anna Bratek-Skicki, Ludo Van Den Bosch, Yves Moreau, Frederic Rousseau, Joost Schymkowitz
    Bioinformatics . 2021 May 13;btab350
    PubMed
  • publication

    Liquid-Liquid Phase Separation Enhances TDP-43 LCD Aggregation but Delays Seeded Aggregation

    Donya Pakravan, Emiel Michiels, Anna Bratek-Skicki, Mathias De Decker, Joris Van Lindt, David Alsteens, Sylvie Derclaye, Philip Van Damme, Joost Schymkowitz, Frederic Rousseau, Peter Tompa, Ludo Van Den Bosch
    Biomolecules . 2021 Apr 8;11(4):548
    PubMed