Biophysics Platform
The Switch Laboratory established the expertise platform Molecular Biophysics Leuven, an interest platform of KULeuven-based research groups that utilise molecular biophysical techniques and instruments in their daily research.
Typically measured is protein folding, conformation and stability, as well as interactions betweens proteins, DNA and other biomolecules.
Much of the equpiment below is now incorporated in the Biophysics Expertise Unit of the VIB-KU Leuven Center for Brain and Disease Research.
The expertise unit hosts state-of-the-art equipment and a dedicated unit leader to offer expertise and training to other research groups.
Equipment

Protein-protein interaction
Biolayer Interferometry

Protein-protein interaction
Grating-Coupled Interferometry

Plate readers
Full Spectrum Fluorescence

Plate Readers
Multi-mode plate reader

Particle sizing
Dynamic Light Scattering

Plate Readers
Polarisation anisotropy plate reader

Conformational analysis
Fourier transform infrared spectroscopy

Protein stability and aggregation
Intrinsic fluorescence and static light scattering

Sample prep
Precision shearing (sonication)

Sample prep
Pipetting robot

Protein-protein interaction
Thermophoresis

Particle sizing
Multi-angle light scattering

Conformational analysis
Protein Stability

Protein-protein interaction
In-solution Biophysics

Ultrastructure
Bio-AFM

Ultrastructure
AFM-IR Nanoscale IR Spectroscopy System