Mapping aggregation-specific interactions in human disease

Newest publications

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  Toward a thermodynamic taxonomy of amyloid fibrils

  Nikolaos Louros, Joost Schymkowitz, Frederic Rousseau

  Structure 2025 Oct 2

  PubMed
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  [11C]HSP990 PET as a translational tool to investigate the role of Hsp90 in tumours and support the development of Hsp90 therapeutics

  Romy Cools, Valeria Narykina, Koen Vermeulen, Sanket J Mishra, Brian S J Blagg, Marleen Derweduwe, Frederik De Smet, Aaron Ziani-Zeryouh, Matteo Riva, An Coosemans, Frederic Rousseau, Joost Schymkowitz, Guy Bormans

  EJNMMI Radiopharm Chem. 2025 Sep 26

  PubMed
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  AXZ viewer: a web application to visualize unprocessed AFM‑IR data

  Wouter Duverger, Georg Ramer, Nikolaos Louros, Joost Schymkowitz, Frederic Rousseau

  Bioinformatics 2025 Sep 19

  PubMed
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  Chemical Synthesis of Medin via a Removable Aggregation-Suppressing Linker

  Matthias De Vleeschouwer, Brajabandhu Pradhan, Frederic Rousseau, Joost Schymkowitz

  J Pept Sci 2025 Aug

  PubMed
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  Mimicking the structure and function of tau folds associated with disease

  Joost Schymkowitz & Frederic Rousseau

  Nat Chem . 2025 May 23

  PubMed
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  Directed disruption of IL2 aggregation and receptor binding sites produces designer biologics with enhanced specificity and improved production capacity

  Amy Dashwood, Ntombizodwa Makuyana, Rob van der Kant, Arman Ghodsinia, Alvaro R Hernandez, Stephanie Lienart, Oliver Burton, James Dooley, Magda Ali, Lubna Kouser, Francisco Naranjo, Matthew G Holt, Frederic Rousseau, Joost Schymkowitz, Adrian Liston

  Comput Struct Biotechnol J . 2025 Mar

  PubMed