Newest publications
Directed disruption of IL2 aggregation and receptor binding sites produces designer biologics with enhanced specificity and improved production capacity
Amy Dashwood, Ntombizodwa Makuyana, Rob van der Kant, Arman Ghodsinia, Alvaro R Hernandez, Stephanie Lienart, Oliver Burton, James Dooley, Magda Ali, Lubna Kouser, Francisco Naranjo, Matthew G Holt, Frederic Rousseau, Joost Schymkowitz, Adrian Liston
Comput Struct Biotechnol J . 2025 Mar
PubMedCharting the structure-sequence landscape of light chain amyloids
Gabriele Orlando, Rodrigo Gallardo, Alicia Colla, Joost Schymkowitz, Frederic Rousseau
Bioinformatics 2025 Apr
PubMedTDP-43 seeding induces cytoplasmic aggregation heterogeneity and nuclear loss of function of TDP-43
Jens Rummens, Bilal Khalil, Günseli Yıldırım, Pedro Silva, Valentina Zorzini, Nicolas Peredo, Marta Wojno, Meine Ramakers, Ludo Van Den Bosc, Philip Van Damme, Kristofer Davie, Jelle Hendrix, Frederic Rousseau 7, Joost Schymkowitz, Sandrine Da Cruz
Neuron 2025 Mar 26
PubMedImpact of amyloid-like ovalbumin fibril consumption on health-related markers: An in vitro approach
Trui Luyckx, Charlotte Grootaert, Jan A. Delcour, Joëlle A.J. Housmans, Frederic Rousseau, Joost Schymkowitz, Sebastien Carpentier, John Van Camp
Food Research International vol 208
PubMedDevelopment and evaluation of Hsp90-targeting nanobodies for visualisation of extracellular Hsp90 in tumours using PET imaging
Valeria Narykina, Janke Kleynhans, Christopher Cawthorne, Joost Schymkowitz, Frederic Rousseau, Guy Bormans
EJNMMI Radiopharm Chem . 2025 Feb 21
PubMedNative Fold Delay and its implications for co-translational chaperone binding and protein aggregation
Ramon Duran-Romaña, Bert Houben, Paula Fernández Migens, Ying Zhang, Frederic Rousseau, Joost Schymkowitz
Nat Commun . 2025 Feb 15
PubMed
