Biophysics Platform
The Switch Laboratory established the expertise platform Molecular Biophysics Leuven, an interest platform of KULeuven-based research groups that utilise molecular biophysical techniques and instruments in their daily research.
Typically measured is protein folding, conformation and stability, as well as interactions betweens proteins, DNA and other biomolecules.
Switch hosts state-of-the-art equipment and offers expertise and training to other research groups.
https://gbiomed.kuleuven.be/english/networks/molecular-biophysics
Equipment
![laboratory - Protein-protein interaction](/static/9e17e3d4e3a65e7fb8c4bba967e24fc9/cd83f/fullwidth.jpg)
Protein-protein interaction
Biolayer Interferometry
![laboratory - Particle sizing](/static/78605794bcc08fdd992ede6fa07a3ae0/14b42/dynapro-plate-reader-iii-product.jpg)
Particle sizing
Dynamic Light Scattering
![laboratory - Conformational analysis](/static/21d2187e23091a31844fa4b8c31278ba/356ca/ftir.jpg)
Conformational analysis
Fourier transform infrared spectroscopy
![laboratory - Plate Readers](/static/21d0405edecc566df94777c71f1fbfd3/c11ac/fluostar.png)
Plate Readers
Multi-mode plate reader
![laboratory - Plate readers](/static/5847cd593b91eb977058b970f183d75e/c11ac/clario.png)
Plate readers
Full Spectrum Fluorescence
![laboratory - Particle sizing](/static/4c8d63796b0cef419ca51695420ec5af/14b42/img_7444.jpg)
Particle sizing
Multi-angle light scattering
![laboratory - Plate Readers](/static/45e79af97da224f6824817d806b49949/c11ac/polarstar.png)
Plate Readers
Polarisation anisotropy plate reader
![laboratory - Sample prep](/static/b6c5db602308545a9930f645c5099b47/ec9fc/screenshot-2022-01-18-at-11.04.12.png)
Sample prep
Biorupter Pico
![laboratory - Protein-protein interaction](/static/39ab0cfea8ee4d364f831609761208b4/c2c47/monolith.jpg)
Protein-protein interaction
Thermophoresis
![laboratory - Protein stability and aggregation](/static/b71f06df1c5a0ade29c35bef8da7614f/c1b5f/uncle-2.png)
Protein stability and aggregation
Intrinsic fluorescence and static light scattering
![laboratory - Ultrastructure](/static/3fea5142960e19aeaa609acdaf2b8d69/63919/screenshot-2021-03-18-at-15.26.01.png)
Ultrastructure
Bio-AFM
![laboratory - Ultrastructure](/static/b25dda0c8f42c7ed34d0e61cf681f8dd/35c37/nano.jpg)
Ultrastructure
AFM-IR Nanoscale IR Spectroscopy System